Selected Publications by lab members

• Gene activity fully predicts transcriptional bursting dynamics
  Po-Ta Chen*, Michal Levo*, Benjamin Zoller*, Thomas Gregor.
  arXiv. 2024

• Transcriptional coupling of distant regulatory genes in living embryos
  Michal Levo*, João Raimundo*, Xin Yang Bing, Zachary Sisco, Philippe J. Batut, Sergey Ryabichko, Thomas Gregor, Michael S. Levine.
  Nature. 2022

• Dynamic interplay between enhancer-promoter topology and gene activity
  Hongtao Chen, Michal Levo, Lev Barinov, Miki Fujioka, James B. Jaynes, Thomas Gregor.
  Nature Genetics. 2018

• Systematic investigation of transcription factor activity in the context of chromatin using massively parallel DNA binding and expression assays
  Michal Levo, Tali Avnit-Sagi, Maya Lotan-Pompan, Yael Kalma, Adina Weinberger, Zohar Yakhini, Eran Segal.
  Molecular Cell. 2017

• Unraveling determinants of transcription factor binding outside the core binding site
  Michal Levo*, Einat Zalckvar*, Eilon Sharon, Ana Carolina Dantas Machado, Yael Kalma, Maya Lotam-Pompan, Adina Weinberger, Zohar Yakhini, Remo Rohs, Eran Segal.
  Genome Research. 2015

• In pursuit of design principles of regulatory sequences
  Michal Levo and Eran Segal.
  Nature Reviews Genetics. 2014

• Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast
  Tali Raveh-Sadka*, Michal Levo*, Uri Shabi, Boaz Shany, Leeat Keren, Maya Lotan-Pompan, Danny Zeevi, Eilon Sharon, Adina Weinberger, Eran Segal.
  Nature Genetics. 2012

• Incorporating Nucleosomes into Thermodynamic Models of Transcription Regulation
  Tali Raveh-Sadka*, Michal Levo*, Eran Segal.
  Genome Research. 2009

Additional Publications by lab members

• Functional analysis of the Drosophila eve locus s in response to non-canonical combinations of gap gene expression levels
  Netta Haroush, Michal Levo, Eric Wieschaus, Thomas Gregor.
  Developmental Cell. 2023

• Genome organization controls transcriptional dynamics during development
  Philippe J. Batut, Xin Yang Bing, Zachary Sisco, João Raimundo, Michal Levo, Michael S. Levine.
  Science. 2022

• SnapShot: The Regulatory Genome
  Xin Yang Bing, Philippe J. Batut, Michal Levo, Michael S. Levine, João Raimundo.
  Cell. 2020

• Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise
  Maya Dadiani, David van Dijk, Barak Segal, Yair Field, Gil Ben-Artzi, Tali Raveh-Sadka, Michal Levo, Irene Kaplow, Adina Weinberger, Eran Segal.
  Genome Research. 2013

• Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters
  Eilon Sharon*, Yael Kalma*, Ayala Sharp, Tali Raveh-Sadka, Michal Levo, Danny Zeevi, Leeat Keren, Zohar Yakhini, Adina Weinberger, Eran Segal.
  Nature Biotechnology. 2012

• Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters
  Danny Zeevi*, Eilon Sharon*, Maya Lotan-Pompan, Yaniv Lubling, Zohar Shipony, Tali Raveh-Sadka, Leeat Keren, Michal Levo, Adina Weinberger, Eran Segal.
  Genome Research. 2011
  

• Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation
  Ophir Shalem, Orna Dahan, Michal Levo, Maria Rodriguez Martinez, Itay Furman, Eran Segal, Yitzhak Pilpel.
  Molecular Systems Biology. 2008